Scintigraphic Evaluation of Regional Pulmonary Circulation and Ventilation Abnormalities in Mitral Valvelar Disease and Congestive Heart Failure : The Present Status of Cordiovascular Nuclear Medicine

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Regional pulmonary mean transit time, MTT (RV-Lung) was measured by radionuclide angiography using ^<99m>Tc-pertechnetate or ^<99m>Tc-HSA. In 8 normal subjects, MTT (RV-Lung) in upper (U) and lower (L) lung fields averaged 2.48 and 2.81 sec, respectively. In MS and CHF groups, MTT (RV-Lung) in L was markedly prolonged (5.04 and 5.10 sec, respectively) and after appropriate medical or surgical treatment, MTT in L markedly reduced. Pulmonary ventilation perfusion scintigraphy with ^<133>Xe was performed in 18 patients with MS. Both Vu/L and Qu/L increased in accordance with the severity of disease, however, Vu/L had never exceeded unity. The estimation of regional MTT in the lung field is to be useful way in evaluating the severity of pulmonary circulatory disturbance in MS or in congestive heart failure.
社団法人日本循環器学会の論文
1981-01-20