PHARMACOLOGICAL AND ELECTROPHYSIOLOGICAL ACTIONS OFPROSCILLARIDIN A THE MECHANISM OF BIGEMINAL RHYTHM INDUCED BY ITS TOXIC DOSAGE STUDIED BY THE CHANGE OF THE TRANSMEMBRANE ACTION POTENTIAL
スポンサーリンク
概要
- 論文の詳細を見る
The mechanism of the bigeminal rhythm induced by the toxic dose of rapid acting unique cardiac glycoside; Proscillaridin A, was investigated by means of the intracellular microelectrode technique, upon the guinea pig ventricular fibers, and the clinical case record of bigeminal rhythm induced by its intoxication was also analysed. On the experimental finding, the bigeminal rhythm appeared when the repolarization phase 2 was decreased about 40%. Clinically, the plethysmographic finding may be the good parameter to judge the appropriate dosage of Proscillaridin A for its maintenance dose for every individual patient.
- 社団法人日本循環器学会の論文
- 1971-12-20
著者
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Kobayashi Toshiji
Department Of Internal Medicine National Cancer Hospital
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NAKAYAMA RYU
Department of Medical Cardiology, National Cardiovascular Center
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Nakayama Ryu
Department Of Internal Medicine National Cancer Hospital
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Kimura Kiyoji
Department of Internal Medicine, National Cancer Hospital
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TAKATANI OSAMU
Department of Internal Medicine, National Cancer Center Hospital
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Kimura Kiyoji
Department Of Internal Medicine National Cancer Hospital
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Takatani Osamu
Department Of Internal Medicine National Cancer Center Hospital
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KIMURA Kiyoji
Department of Clinical Oncology, Nagoya Memorial Hospital
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- PHARMACOLOGICAL AND ELECTROPHYSIOLOGICAL ACTIONS OFPROSCILLARIDIN A THE MECHANISM OF BIGEMINAL RHYTHM INDUCED BY ITS TOXIC DOSAGE STUDIED BY THE CHANGE OF THE TRANSMEMBRANE ACTION POTENTIAL
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