Measurement of Cerebral Blood Flow by Ultrasonic Doppler Technique Hemodynamic Correlation Between Cerebral and Peripheral・ophthalmic Artery

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Half a century has passed since KOROTKOW discovered that the vascular sound became audible when pressure was added around the arm by tourniquet and he published that this phenomenon could be applied to the measurement of the systolic and diastolic blood pressures. Even at the present stage, there is no better method of measuring blood pressure with an exception of arterial puncture. In this paper, spectro-analytic studies been done on the characters of the KOROTKOW sounds, and some characteristic of the KOROTKOW sounds in normal subjects and diseases were found out. The hemodynamic factors affecting the KOROTKOW sounds were also discussed. Method and Materials Twenty seven cases, aging from 20 to 78 years old, (25 males, 2 females) were studied. They were consisted of 10 normal subjects ECG and the beginning of the KOROTKOW (Group I), 6 patients with essential hypertension (Group II), 6 with arteriosclerosis (Group III) and 5 with aortic insufficiency (Group IV). The upper arm was surrounded by the ordinary cuff. Moving coil microphone was attached on the surface of the cubital joint with constant pressure. The KOROTKOW sounds were recorded with phonocardiograph, which characteristics was flat in the range from DC to 1000 cps. The pressure patterns were recorded with Statham P-23 Db pressure transducer connected with REILEY'S indwelling needle on just peripheral site of the microphone. The KOROTKOW sounds, pressure patterns ofbrachial artery and ECG (Standard limb lead II) were recorded simultaneously with the tape recorder during decreasing the cuff pressure (Fig. 1). Then, the KOROTKOW sounds were spectroanalysed in the range of 28 to 450 cps by the band pass filter, which were divided into 12 frequency bands by 1/3 oct. step. The maximal amplitude in each frequency of the sounds was measured in each beat. Amplitude-frequency relationships of the above 4 groups were compared. Maximal amplitude in each case was set to 100 per cent and the other amplitudes were expressed in percentage. The Q-K time (time interval between Q in ECG and the beginning of the KOROTKOW sounds) was measured. The first and second derivatives of brachial arterial pressure pattern were obtained by analogue computer and their peak values and the time interval between Q in ECG and the peak values were measured.
社団法人日本循環器学会の論文
1966-11-20

Measurement of Cerebral Blood Flow by Ultrasonic Doppler Technique Hemodynamic Correlation Between Cerebral and Peripheral・ophthalmic Artery

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