THE HYPOTENSIVE EFFECT OF FUSARIC ACID : THE RESULTS OF LONG-TERM ADMINISTRATION OF FUSARIC ACID IN ELDERLY HYPERTENSIVE PATIENTS

スポンサーリンク

概要

• 論文の詳細を見る

• The hypotensive effect of fusaric acid calcium salt (Calcium salt of 5-butylpicolinic acid) was examined clinically in 10 elderly hypertensive patients by the long-term administration of this agent and the following results were obtained. 1) The means of the systolic and/or diastolic blood pressures of each patient were significantly lower during the first year of the trial period than those during the one year's control period in all patients. 2) The means of the systolic and/or diastolic blood pressures of each patient were significantly lower during the second year of the trial period than those during the one year's control period, in whom administration of fusaric acid calcium salt was continued throughout two years. A significant reduction of the systolic blood pressure was observed in 3 out of 6 patients and that of the diastolic blood pressure was observed in 5 out of 6 patients. 3) Comparison was made between the means of the systolic and diastolic blood pressures during the one year's control period and those during the six months' placebo period after two year's administration of fusaric acid calcium salt. During the placebo period, both systolic and diastolic blood pressures showed a tendency of returning to the levels during the control period, confirming the hypotensive effect of this agent. 4) Laboratory findings after one year's administration of fusaric acid calcium salt showed no adverse effect of this agent.

• 社団法人日本循環器学会の論文
• 1976-10-20

著者

• TERASAWA FUJIO

  The 3rd Department of Internal Medicine, Faculty of Medicine, University of Tokyo and the Yokugukai

• Hon Ying

  The Yokufukai Geriatric Hospital

• Terasawa Fujio

  The 3rd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo

• KAMEYAMA Masakuni

  The Department of Internal Medicine

• Kameyama Masakuni

  The Department Of Geriatrics Faculty Of Medicine University Of Kyoto

• Ying Lie

  The Yokufukai Geriatric Hospital

関連論文

• VECTORCARDIOGRAMS OF ELECTROCARDIOGRAPHIC INCOMPLETE LEFT BUNDLE BRANCH BLOCK
• Preclinical Cushing's Syndrome due to Adrenocorticotropin-Independent Bilateral Adrenocortical Macronodular Hyperplasia with Concurrent Excess of Gluco- and Mineralocorticoids
• Pressoreflex Arising from the Left Coronary Artery
• Phlebosclerosis of the Colon with Positive Anti-Centromere Antibody
• URINARY NOREPINEPHRINE EXCRETION IN ELDERLY HYPERTENSIVE PATIENTS DURING ADMINISTRATION OF FUSARIC ACID
• THE LONG-TERM HEMODYNAMIC EFFECT OF FUSARIC ACID IN ELDERLY HYPERTENSIVE PATIENTS
• THE HYPOTENSIVE EFFECT OF FUSARIC ACID : THE RESULTS OF LONG-TERM ADMINISTRATION OF FUSARIC ACID IN ELDERLY HYPERTENSIVE PATIENTS
• TIME0URSE CHANGES IN BLOOD PRESSURE, URINARY EXCRETION OF NOREPINEPHRINE AND DOPAMINE AFTER ADMINISTRATION OF FUSARIC ACID IN A SINGLE DOSE IN ELDERLY HYPERTENSIVE PATIENTS

スポンサーリンク