PREVENTIVE EFFECT OF EXERCISE TRAINING ON RECURRENT STENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY(PTCA)

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概要

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• The purpose of this study is to evaluate whether exercise trainig for 12 weeks prevents the development of restenosis after percutaneous transluminal coronary angioplasty (PTCA). Symptom-limited treadmill exercise with thallium-201 myocardial single photon emission computed tomography (SPECT) was performed one and 13 weeks after PTCA in 18 patients with exercise training and in 20 patients with-out. For quantitative analysis, the average count of region of interest in the hypoperfused area on the polar map was calculated. A percentage tl uptake was determined by dividing average count of the hypoperfused area by that of a normal reference area at an initial image (%IU) and a delayed image (%DU). A percentage redistribution (%RD) was obtained by subtracting %IU from %DU as the parameter of residual ischemia in the hypoperfused area. Total treadmill exercise duration and maximal pressure rate product 13 weeks after PTCA increased significantly (p<0.01) in the trained group, whereas there was no significant change in the untrained group. %DU increased significantly (p<0.01) in the trained group, whereas there was no significant change in the untrained group. %RD decreased significantly (p<0.01) in the trained group, whereas there was no significant changes in the untrained group. The restenosis rates at the third month after PTCA was 17% (3/18) in the trained group and 40% (8/20) in the untrained group. These findings suggest that in patients with coronary artery disease exercise training improves myocardial perfusion by preventing the progression of coronary artery stenosis after PTCA.

• 社団法人日本循環器学会の論文
• 1992-05-20

著者

• Yabuki So

  Toho University School Of Medicine Ohashi Hospital Third Department Of Internal Medicine

• YABUKI SO

  The Third Department of Internal Medicine, Ohashi Hospital, Toho University School of Medicine

• HIRAI Hironori

  The Third Department of Internal Medicine,Toho Univrsity Tokyo

• KUBO HIROSHI

  The Third Department of Internal Medicine, Toho University School of Medicine

• YANO KIMIO

  The Third Department of Internal Medicine, Toho University School of Medicine

• MACHII KIYOSHI

  The Third Department of Internal Medicine, Toho University School of Medicine

• Yabuki So

  Third Department Of Internal Medicine Toho University Ohashi Hospital

• Kubo Hiroshi

  The Third Department Of Internal Medicine Toho University School Of Medicine

• Machii Kiyoshi

  The Third Department Of Internal Medicine Toho University School Of Medicine

• Hase Hiroki

  東邦大学医学部第三内科

• Hirai Hironori

  Department Of Cardiovascular Medicine Toho University Ohashi Medical Center

• Suemoto Yoshinobu

  Department Of Cardiology Kawaguchi Municipal Medical Center

• Yabuki Sou

  1st Dept. Of Intern. Med. Toho Univ. School Of Med.

• Hirai Hironori

  3rd. Department Of Internal Medicine Toho University School Of Medicine

• Yabuki So

  Third Department Of Internal Medicine

• Yabuki Sou

  Third Department Of Internal Medicine Toho University Ohashi Hospital

• Yano Kimio

  The Third Department Of Internal Medicine Toho University School Of Medicine

• Yabuki So

  3rd Division Department Of Internal Medicine Toho University Ohashi Hospital

• Machii Kiyoshi

  The 3rd Department Of Internal Medicine Toho University School Of Medicin

• Saito Yoshinori

  Third Department Of Internal Medicine

• Yabuki So

  The Third Dept. Of Int. Med. Toho Univ. School Of Med. .

• Sato Yuichi

  Dept. Of Cardiol. Cedars-sinai Med. Ctr.

• Machii Kiyoshi

  Center For Cardiovasc. Dis. Mitsui Memorial Hosp.

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