DISUSE ATROPHY OF THE LEFT VENTRICLE IN CHRONICALLY BEDRIDDEN ELDERLY PEOPLE
スポンサーリンク
概要
- 論文の詳細を見る
In the elderly cardiac size and function are determined by their level of physical activity. In this study, we assessed by echocardiography, the anatomic and physiologic changes of the heart in 28 elderly patients who had no cardiac disease and who were chronically bedridden. The data obtained were compared to those obtained from a control group of 38 age and sex matched elderly people whose activities had not been restricted. Chronically bedridden patients had markedly smaller left ventricular dimensions in both end-diastole and end-systole and smaller left atrial dimensions than did control subjects (3.7±0.7 vs 4.7±0.6cm, p<0.001, 2.4±0.8 vs 2.9±0.7cm, p<0.02 and 3.2±0.5 vs 3.8±0.9cm, p<0.01, respectively). Though the wall thickness of the interventricular septum did not differ between the study groups, the left ventricular posterior walls of the bedridden group were significantly thinner than in the control group (0.8±0.2 vs 1.0±0.2 cm, p<0.01). The bedridden group had a significantly lower stroke index (26.9±6.2 vs 47.0±11.1 ml/m^2, p<0.001) and cardiac index (1.84±0.52 vs 3.15±0.63 l/min/m^2, p<0.001) than did the control group. Left ventricular mass index and left ventricular systolic stress were significantly lower in bedridden patients than in control subjects (88.0±18.1 vs 143.5±30.9 g/m^2, p<0.001, and 135.9±4.9 vs 186.6±35.7 103 dynes/cm^2, p<0.001, respectively). The shortening fraction, however, did not differ between the two groups. The peak trans-aortic flow velocity of bedridden patients was not different from control subjects. The peak trans-mitral flow velocity in early diastole (R) of bedridden patients was significantly lower than in control subjects(0.44±0.15 vs 0.57±0.20 cm/s, p<0.01), while the decrease in peak trans-mitral flow velocity during atrial systole (A) was not significant. The ratio of A to R was significantly larger in the bedridden group than in the control group (1.8±0.7 vs 1.5±0.5, p<0.05). We conclude that long term bed rest causes disuse atrophy of the heart in the elderly by decreasing venous return, left ventricular work and wall stress.
- 社団法人日本循環器学会の論文
- 1992-03-20
著者
-
Matsubara Kinya
Department of Cardiology, Kyoto City Hospital
-
Nakamura T
Second Department Of Internal Medicine Kyoto Prefectural University Of Medicine
-
Matsubara Kinya
The Department Of Internal Medicine
-
NAKAGAWA Masao
the Second Department of Medicine, Kyoto Prefectural University of Medicine
-
Azuma Aklhiro
Second Department Of Medicine Kyoto Prefectural University Of Medicine
-
Azuma Akihiro
The Second Department Of Medicine Kyoto Prefectural University Of Medicine
-
Sugihara Hiroki
The Second Departement of Medicine, Kyoto Prefectual University of Medicine
-
Furukawa Keizo
The Second Departement of Medicine, Kyoto Prefectual University of Medicine
-
Asayama Jun
The Second Departement of Medicine, Kyoto Prefectual University of Medicine
-
Katsume Hiroshi
The Second Department of Medicine, Kyoto Prefectural University of Medicine
-
Furukawa Keizo
Department Of Cardiology Kyoto City Hospital
-
Nakagawa Masao
The Second Department Of Medicine Kyoto Prefectural University Of Medicine
-
Kunishige Hiroshi
Matsushita Memorial Hospital
-
Nakamura Takashi
The Second Department of Medicine, Kyoto Prefectural University of Medicine
-
Ohtsuki Katsuichi
Meiji University of Oriental Medicine
-
MATSUBARA KINYA
The Second Department of Medicine, Kyoto Prefectural University of Medicine
-
OHNISHI KAZUHIKO
The Second Department of Medicine, Kyoto Prefectural University of Medicine
-
Katsume Hiroshi
Matsushita Memorial Hospital
-
Katsume Hiroshi
The 2nd Department Of Internal Medicine Kyoto Prefectural University Of Medicine
-
Ohnishi Kazuhiko
Meiji University Of Oriental Medicine
-
Katsume Hiroshi
Second Department Of Medicine Kyoto Prefectural University Of Medicine
-
Ohtsuki Katsuichi
Department Of Cardiovascular Medicine
-
Matsubara Kinya
Department Of Cardiology Kyoto City Hospital
-
Nomura Tetsuya
Department Of Cardiovascular Medicine Nantan General Hospital
-
Furukawa Keizo
Department Of Cardiovascular Medicine Social Welfare Organization Imperial Gift Fundation Inc. Saise
-
Shiraishi Hirokazu
京都府立与謝の海病院
-
Hirasaki Satoshi
Department Of Cardioology Matsushita Memorial Hospital
-
Katsume Hiroshi
The 2nd Dept. Of Med. Kyoto Pref. Univ. Of Med.
-
Nakamura Takeshi
Kyoto Prefectural University Of Medicine Department Of Cardiology
-
Furukawa Keizo
Department Of Cardiovascular Medicine Social Welfare Organization Imperial Gift Fundation Inc. Saise
-
Matsubara Kin-ya
Department Of Cardiology Kyoto City Hospital
-
Kunishige Hiroshi
Kyoto Pref. Hosp. Of Yosa No Umi Kyoto Pref. Univ. Of Med. 2nd Intern. Med.
-
Katsume Hiroshi
The Second Department Of Medicine Kyoto Prefectural University Of Medicine
-
Kunishige Hiroshi
2nd Dept. Of Intern. Med. Kyoto Pref. Univ. Of Med.
-
Nakagawa Masao
The Second Department of Internal Medicine, Kyoto Prefectural University of Medicine
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