CLASSIFICATION OF β-BLOCKING AGENTS BY THEIR INHIBITORY EFFECTS ON PHOSPHOLIPASE ACTIVITY

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概要

• 論文の詳細を見る

• The inhibitory effects ofβ-blocking agents against the action of phospholipase (PLase) were investigated. Using micelles of dimyristoyl (-)-α-phosphatidylcholine (DMPC) as a substrate, myristic acid (MA) released from DMPC by PLase A_2 was determined by gas chromatography. β-Blocking agents were divided into 4 groups depending on their inhibitory effects on PLase. Their inhibitory effects on PLase could be due to their displacing ability with Ca^<++> on membrane phospholipids, since Ca^<++> is an essential factor for the activation of PLase.

• 社団法人日本循環器学会の論文
• 1986-03-20

著者

• Ozawa Takayuki

  Faculty Of Medicine University Of Nagoya

• Nagai Shuichiro

  Departments of InternaI Medicine, FacuIty of Medicine, University of Nagoya

• Ozawa Takayuki

  Biomedical Chemistry Faculty Of Medicine University Of Nagoya

• Sugiyama Satoru

  Biomedical Chemistry Faculty Of Medicine University Of Nagoya

• Nagai Shuichiro

  Departments Of Internal Medicine And Biomedical Chemistry

• Ozawa Takayuki

  Departments Of Biomedical Chemistry Faculty Of Medicine University Of Nagoya

• Ozawa Takayuki

  The Department Of Biomedical Chemistry Faculty Of Medicine University Of Nagoya

• Sugiyama Satoru

  Biomedical Chemistyry Faculty Of Medicine University Of Nagoya

• Sugiyama Satoru

  Departments Of Biomedical Chemistry Faculty Of Medicine University Of Nagoya

• SUGIYAMA SATORU

  Faculty of Medicine, University of Nagoya

• Ozawa T

  The Department Of Biomedical Chemistry Faculty Of Medicine University Of Nagoya

• Sugiyama Satoru

  Faculty Of Medicine University Of Nagoya

• Ozawa Takayuki

  Departments Of Biomedical Chemistry University Of Nagoya

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