SERUM ENZYMES IN THE DIFFERENTIAL DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION
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概要
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The paper describes the various serum enzyme patterns, the H-type of SLDH (serum lactate dehydrogenase) isoenzymes with special reference to their differences in acute myocardial infarction, cerebrovascualr disease, renal failure, and megaloblastic anemia. Characteristic differences in the patterns of change in the various serum enzymes were noted in these diseases. In the acute myocardial infarction group, the H-type pattern of SLDH isoenzymes appeared in 94.4%, and SLDH, SGOT, and SCPK activities were elevated in all cases. In the cerebrovascular disease group, the H-type pattern of SLDH isoenzymes appeared in 66.7% of the patients, and there were elevations of SLDH in 37.8%, SCPK in 69.7%, and SGOT in 43.1%. In this group, the peak values of both SCPK (serum creatine phosphokinase) and the H-type of SLDH isoenzymes were reached about 3-5 days after the onset of symptoms, and the SCPK level returned to normal more slowly. The rate of increase of total SLDH activity and the LD5/LD4 ratio of SLDH isoenzymes were generally lower than in the acute myocardial infarction group. The amount of total SLDH activity was also less and in some ceases did not increase in this group. In the renal failure group, H-type pattern of SLDH isoenzymes appeared in 33.0% of the patients, and in many cases (75% of the patients) there was an elevation of SCPK activity; the reason for this phenomenon must be investigated. The SGOT an SGPT activities remained almost within the normal range in most of the patients in this group. Both patients with megaloblastic anemia showed a clear H-type pattern of SLDH isoenzymes, but there was no elevation of SCPK, or SGOT and SGPT activities. SLDH activity, however, was normal in one case, and markedly increased in the other.
- 社団法人日本循環器学会の論文
- 1978-10-20
著者
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Konno Sen-ichiro
Kyoto Medical Association For Prevention Of Cardiovascular Disease
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Kiyomi Sadamichi
Tokyo Medical College
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Yamasawa Ikuhiro
The 2nd Dept. Of Intern.med. Tokyo Medical College
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Kaneko Yoshinobu
Hachioji Medical Center
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Yaoita Nobutaka
Hachioji Medical Center
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Morimoto Michinari
The Dept. Of Intern. Med. Shinko Hospt.
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KIYOMI Sadamichi
The 2nd Department of Internal Medicine,Tokyo Medical College
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Minami Hiroshi
Tokyo Medical College, 2nd Dept. of Internal Medicine
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NAGAI Yoshikazu
The 2nd Dept. of Intern.Med. , Tokyo medical College
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Takahashi Hajime
The 2nd Dept.of Intern. Med., Medical College
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Minami Hiroshi
The 2nd Dept.of Intern. Med., Medical College
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Amari Hideo
The 2nd Dept.of Intern. Med., Medical College
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Yaoita Nobutaka
The 2nd Dept.of Intern. Med., Medical College
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Kaneko Yoshinobu
The 2nd Dept.of Intern. Med., Medical College
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KONNO SEN-ICHIRO
The 2nd Dept. of Intern. Med., Tokyo Medical College
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SAKOTA EIKO
The 2nd Dept. of Intern. Med., Tokyo Medical College
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TSUBOUCHI KENJI
The 2nd Dept. of Intern. Med., Tokyo Medical College
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NOHARA YOSHITSUGU
The 2nd Dept. of Intern. Med., Tokyo Medical College
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Nagai Yoshikazu
Second Department Of Internal Medicine Tokyo Medical University
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Nohara Yoshitsugu
Department Of Internal Medicine Tokyo Medical College
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Yamasawa Ikuhiro
Kyoto Medical Association For Prevention Of Cardiovascular Disease The 2nd Dept Of Intern. Med. Toky
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Nohara Yoshitsugu
The 2nd Department Of Internal Medicine Tokyo Medical College
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Nohara Yoshitsugu
The Hachiohji Medical Center Tokyo Medical College
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Sakota Eiko
The 2nd Dept. Of Intern. Med. Tokyo Medical College
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Amari Hideo
The 2nd Dept.of Intern. Med. Medical College
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Nohara Yoshitsugu
Department Of Internal Hedicine (divfsion 1]) Tokyo Medical College
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Nohara Yoshitsugu
3rd Dept. Of Intern. Med. Kyoto Univ. School Of Med.
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Tsubuchi Kenji
The 2nd Dept.of Intern. Med. Medical College
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Nohara Yoshitsugu
Kyoto Medical Association For Prevention Of Cardiovascular Disease
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Yamasawa Ikuhiro
The 2nd Department Of Internal Medicine Tokyo Medical College
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Konno Senichiro
The 2nd Dept.of Intern. Med. Medical College
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Yaoita Nobutaka
The 2nd Department Of Internal Medicine Tokyo Medical College
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Nohara Yoshitsugu
The 3rd Division Department Of Internal Medicine School Of Medicine Kyoto University
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MATSUMOTO HIDETOSHI
The Dept. of Intern. Med. . Shinko Hosp.
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Nohara Yoshitsugu
Department Of Internal. Medicine Kyoto University School Of Medicine
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Yamasawa Ikuhiro
Second Department Of Internal Medicine Tokyo Medical College
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Minami Hiroshi
The 2nd Dept. Of Intern. Med. Tokyo Medical College
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Nagai Yoshikazu
The 2nd Dept. Of Intern.med. Tokyo Medical College
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Kiyomi Sadamichi
The 2nd Dept. Of Intern.med. Tokyo Medical College
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Kiyomi Sadamichi
The 2nd Department Of Internal Medicine Tokyo Medical College
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Konno Sen-ichiro
The 2nd Department Of Internal Medicine Tokyo Medical College
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Takahashi Hajime
Department Of Cardiology Tokyo Medical College Kasumigaura Hospital
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