Comparison of Filled-in Myocardial Segments After Early and Late Reinjection of Thallium-201 : Influence of the Timing of Reinjection on Fill-in
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概要
- 論文の詳細を見る
Thallium-201 (^<201>Tl) late reinjection after stress-redistribution imaging improves thc detection of viable myocardium. Recently, early reinjection of ^<201>Tl immediately after stress imaging was proposed as a new method for distinguishing ischemic myocardium, hibernating myocardium, and myocardial scar. However, there are no data on the influence of the timing of reinjection on "fill-in." This study was designed to assess whether the reinjection time influences "fill-in" in chronic coronary artery disease. Thirty-three patients with chronic coronary artery disease were studied. All patients underwent exercise ^<201>Tl tomography. Immediately after stress imaging, 37 MBq of thallium was reinjected earlier than usual and early reinjection delayed image (ERDI) was acquired 3 h later. With the same protocol, all patients also underwent a second study involving late reinjection of ^<201>Tl within 1 week. An additional 37 MBq of thallium was reinjected 3 h after stress imaging, and late reinjection delayed image (LRDI) was obtained 10 min later. All images were analyzed qualitatively using a 4-point grading uptake score. Of the 72 hypoperfused segments on stress images, 66 segments showed fill-in and 6 showed persistent defects on ERDI, and of the same 72 segments 55 segments displayed fill-in and the remaining 17 showed persistent defects on LRDI (p<0.05). The delta uptake score (the uptake score of the delayed image minus that of stress image) in early reinjection was 1.60±0.80, which was significantly higher than that in late reinjection (1.24±0.94, p<0.01). A small dose of thallium reinjected immediately after stress imaging with delayed images obtained 3 h later is convenient and might provide another technique for determining myocardial viability.
- 社団法人日本循環器学会の論文
- 1998-02-20
著者
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YOSHIDA Hiroshi
Department of Clinical Laboratory Medicine, Fukushima Medical College
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Sakata Kazuyuki
Department Of Cardiology Shizuoka General Hospital Shizuoka
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Sakata Kazuyuki
Department Of Nuclear Medicine Shizuoka General Hospital
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Sakata Kazuyuki
The Department Of Cardiology Shizuoka General Hospital
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Sakata Kazuyuki
Department Of Cardiology Shizuoka General Hospital
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Shirotani Manabu
Department of Cardiology, Nara Hospital, Kinki University School of Medicine
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Shirotani Manabu
Department Of Cardiology Nara Hospital Kinki University School Of Medicine
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Shirotani Manabu
The Department Of Cardiology Shizuoka General Hospital
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Yoshida Hiroshi
Department Of Biophysics Graduate School Of Science Kyoto University
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Mochiduki Mamoru
Department of Nuclear Medicine, Shizuoka General Hospital
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Mochiduki Mamoru
Department Of Nuclear Medicine Shizuoka General Hospital
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Yoshida Hiroshi
Department Of Cardiology Shizuoka General Hospital
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Yoshida Hiroshi
The Department Of Cardiology Shizuoka General Hospital
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Yoshida Hiroshi
Departmen Of Radiology School Of Medicine Asahikawa Medical University
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