放射線橋かけポリビニルアルコールハイドロゲルの熱安定性

概要

論文の詳細を見る
The effect of heating on the radiation crosslinking behavior or poly(vinyl alcohol)film(PVA obtained by drying an aqueous solution of PVA)has been studied. For use as medical polymer, the heat stability of crosslinked PVA hydrogel prepared by water immersing has been investigated. Tensile strength reduction of hydrogel by irradiation was inhibited ever though PVA film heated before irradiation required a longer dose for crosslinking than that without heating. The tensile strength before 100℃ sterilization(boiling water)of hydrogel(obtained by 200 kGy irradiation of after heating)was approximately 100 kg/cm^2. The tensile strength of hydrogel reduced by 100℃ sterilization is due to destruction of hydrogen bonds. However, no dissolution and decomposition in this hydrogel were observed after 15 min at 100℃ sterilization. The original shape of hydrogel before water boiling was maintained, althougth some swelling did occur. This hydrogel had higher elastic properties even after boiling.
日本医療機器学会の論文
1992-06-01