栓球による血管内性抗原抗体反応に関する研究 : 第1編逆アナフィラキシー時の肺臓及び心臓の組織学的変化

概要

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The experiment was carried out on the intravascular antigen-antibody reaction induced by injecting the anti-rabbit thrombocyte guinea pig serum into the marginal ear vein of rabbit. Rabbits were autopsied from two hours to thirty days after the provocative injection, and the hematological changes and the histological changes of the lung and heart was examined periodically. The results indicate that thrombocyte count decreased remarkably one or two hours after the provocative injection, and then it was recovered gradually to normal level. Microscopicopically, the hemorrhagic necrotic foci of the lung was observed and the pulmonary vessels revealed cardinal pathological changes such as marked proliferation of the arterial endothelial cells and numerous thrombosis. The hemorrhage, necrosis and proliferation of connective tissues were also revealed in the heart.
日本アレルギー学会の論文
1961-05-30