Checkpoints in B cell development

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概要

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関連論文

Identification of CD19-B220^+ c-Kit^+ Flt3/Flk-2^+ cells as early B lymphoid precursors before pre-B-I cells in juvenile mouse bone marrow
Profound reduction of mature B cell numbers, reactivities and serum lg levels in mice which simultaneously carry the XID and CD40 deficiency genes
Re-evaluation of the probabilities for productive rearrangements on the κ and λ loci
Checkpoints in B cell development
Fetal liver organ cultures allow the proliferative expansion of pre-B receptor-expressing pre-B-II cells and the differentiation of immeture and meture B cells in vitro
Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in V_-deficient mice
The status of lg loci rearrangements in single cells from different stages of B cell development
Iduction of sterile transcription from the κL chain gene locus in V(D)J recombinase-deficient progenitor B cells

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