Fetal liver organ cultures allow the proliferative expansion of pre-B receptor-expressing pre-B-II cells and the differentiation of immeture and meture B cells in vitro

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概要

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著者

• Melchers Fritz

  Basel Institute For Immunology

• Melchers Fritz

  Basel Institure For Immunology Grenzacherstrasse 487

• Andersson Jan

  Basel Institute For Immunology

• BOEKEL Edwin

  Basel Institute for Immunology, Basel, Switzerland

• CEREDIG Rhodri

  Basel Institute for Immunology

• ROLINK Autonius

  Basel Institute for Immunology

• Boekel Edwin

  Basel Institute For Immunology

関連論文

• Identification of CD19-B220^+ c-Kit^+ Flt3/Flk-2^+ cells as early B lymphoid precursors before pre-B-I cells in juvenile mouse bone marrow
• Profound reduction of mature B cell numbers, reactivities and serum lg levels in mice which simultaneously carry the XID and CD40 deficiency genes
• Checkpoints in B cell development
• Fetal liver organ cultures allow the proliferative expansion of pre-B receptor-expressing pre-B-II cells and the differentiation of immeture and meture B cells in vitro
• Partial block in B lymphocyte development at the transition into the pre-B cell receptor stage in V_-deficient mice
• The status of lg loci rearrangements in single cells from different stages of B cell development
• Iduction of sterile transcription from the κL chain gene locus in V(D)J recombinase-deficient progenitor B cells

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