Parameter Identification for Respiratory Dynamics by Personalized Simulation and Experiment

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概要

• 論文の詳細を見る

• Gas flow in the airway and lung deformation due to tissue elasticity and surface tension are the main characteristics of respiratory dynamics. In this study, a simulation with the discretized model as a distributed parameter system is used extensively to identify some of the model parameters which could not be measured directly, and to estimate the real situation of lung respiration. With the use of 5 excised lungs from Japanese white rabbits, the pleural pressure vs lung volume change (P_<pl>-ΔV) relations are observed in situ under oscillating pleural pressure. The elastic properties of the lung tissue are measured under biaxial tension. The unknown parameters, such as that for the surface tension in the alveoli, are identified so that the P_<pl>-ΔV relations calculated by the simulation coincide with the experimental ones for an individual lung. The simulation studies with identified parameters demonstrate potential for estimation of the actual phenomena inside of an excised lung.

• 社団法人日本機械学会の論文
• 1992-04-15

著者

• Tanaka M

  Department Of Surgery And Oncology Graduate School Of Medical Sciences Kyushu University

• Wada Shigeo

  Faculty Of Science And Technology Ryukoku University

• SEGUCHI Yasuyuki

  Formerly, Faculty of Engineering Science, Osaka University

• TANAKA Masao

  Faculty of Engineering Science, Osaka University

• MATSUDA Mitsumasa

  Graduate School of Science and Technology, Kobe University

• ADACHI Taiji

  Division for Research of Engineering Science,Graduate School of Osaka University

• FUJIGAKI Motoharu

  Division for Research of Engineering Science,Graduate School of Osaka University

• Wada Shigeo

  Faculty Of Science And Engineering Tokyo Denki University

• Adachi T

  Osaka Univ. Osaka

• Matsuda Mitsumasa

  Graduate School Of Science And Technology Kobe University

• Seguchi Y

  Formerly Faculty Of Engineering Science Osaka University

• Fujigaki Motoharu

  Division For Research Of Engineering Science Graduate School Of Osaka University

• Adachi Taiji

  Division For Research Of Engineering Science Graduate School Of Osaka University

• Tanaka Masao

  Faculty Of Engineering Science : Osaka University

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