Radiation Protection by Shigoka Extract on Split-Dose Irradiation in Mice
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Radioprotective effect of a Shigoka extract was studied on split-dose irradiation. Mice were exposed to 4 Gy × 4 or 3 Gy × 4 for examining survival ratio or hemogram, respectively. The extract was i. p. injected immediately after each irradiation. The extract significantly (p <0.001) increased the survival ratio, and it increased leukocyte count within the period of the death (days 2-12 after the final exposure). Cerebral hemorrhage after 4 Gy × 4 was diminished by the extract. Recovery of leukocytogenesis seems much more important for survival at split-dose irradiation than at single acute irradiation.
- 日本放射線影響学会の論文
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