Studies on Chemical Protection against Radiation I. The Protective Effect of Orotic Acid against X-Radiation Death in Mice
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概要
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An experiment was carried out to determine the protective effect of orotic acid (uracil-4-carboxylic acid) against X-rays. Orotic acid in dose of 0. 05, 0. 1, 1. 0, 1. 7 and 10 mg per mouse was given intraperitoneally to mice before or after a single dose whole-body X-irradiation of 700 r or 550 r, after which the 30-day survival rate was observed. As a result it was concluded that it would be difficult to state that orotic acid has a protective effect against X-irradiation. It may be added that even if a protective effect exists it would be slight.
- 日本放射線影響学会の論文
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