Germinoma of the Medulla Oblongata : Case Report
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概要
- 論文の詳細を見る
A 32-year-old female presented with medulla oblongata germinoma manifesting as numbness in the extremities. Computed tomography demonstrated a mass in the medulla oblongata expanding into the fourth ventricle. The tumor was partially removed. Immunohistochemical staining of the tumor specimen demonstrated large epithelioid cells positive for placental alkaline phosphatase, and syncytiotrophoblastic cells positive for β subunit of human chorionic gonadotropin. Some epithelioid cells were also positive for cytokeratin. She received 44Gy of irradiation to the posterior fossa and 20Gy whole spinal irradiation. No signs of recurrence have occurred for 9 years. Patients with medulla oblongata germ cell tumor are comparatively older than those with other intracranial germ cell tumors and have two X chromosomes. All tumors were diagnosed as germinoma, and caused symptoms of involvement of the lower cranial nerves and the lower brain stem without pyramidal tract signs.
- 日本脳神経外科学会の論文
- 1994-05-15
著者
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ARITA Kazunori
Department of Neurosurgery, Kagoshima University Faculty of Medicine
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Uozumi Tohru
Department Of Neurosurgery Osaka University Medical School
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SOGABE Takashi
Department of Neurosurgery, Matsuyama Red Cross Hospital
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MAEDA Hitoshi
Department of Legal Medicine, Osaka City University Medical School
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SUGIYAMA Kazuhiko
Department of Neurosurgery, Graduate School of Biomedical Sciences, Hiroshima University
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Sogabe Takashi
Department Of Neurosurgery Matsuyama Red Cross Hospital
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Arita Kazunori
Department Of Earth And Planetary Sciences Hokkaido University
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Arita Kazunori
Department Of Neurosurgery Hiroshima University School Of Medicine
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IKAWA Fusao
Department of Neurosurgery, Shimane Prefecturel Central Hospital
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Uozumi Tohru
Department Of Neurosurgery
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Maeda Hitoshi
Department Of Legal Medicine Osaka City University Medical School
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Sugiyama Kazuhiko
Department Of Neurosurgery Graduate School Of Biomedical Science Hiroshima University
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Ikawa Fusao
Department Of Neurosurgery Hiroshima University School Of Medicine
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GOISHI Junji
Department of Neurosurgery, Matsuyama Red Cross Hospital
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Goishi Junji
Department Of Neurosurgery Matsuyama Red Cross Hospital
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Maeda Hitoshi
Department Of Legal Medicine Kanazawa University School Of Medicine
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Sugiyama Kazuhiko
Department Of Neurosurgerv Facultv Of Medicine Hiroshima University
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Sugiyama Kazuhiko
Department Of Neurosurgery Hiroshima University School Of Medicine:m.d. Division Of Neuropathology D
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Sugiyama Kazuhiko
Department Of Electronic Science And Engineering Kyoto University:crest Japan Science And Technology
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SUGIYAMA Kazuhiko
Department of Clinical Oncology and Neuro-oncology Program, Hiroshima University Hospital
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