β-Tricalcium Phosphate Combined With Recombinant Human Bone Morphogenetic Protein-2 : A Substitute for Autograft, Used for Packing Interbody Fusion Cages in the Canine Lumbar Spine
スポンサーリンク
概要
- 論文の詳細を見る
β-Tricalcium phosphate (β-TCP) combined with recombinant human bone morphogenetic protein-2 (BMP-2) was examined as a substitute for autograft for packing into interbody fusion cages in the canine lumbar spine model. Discectomy and interbody cage fusion were performed at three disc spaces in eight dogs. Examination of microradiographs and histological sections of the lumbar spine at 16 weeks postsurgery revealed three fusions in the autograft cages (Group A), three in the β-TCP cages (Group B), and five in the β-TCP-BMP-2 cages (Group C). The mean percentage of trabecular bone area in the cages was 51.9% in Group A, 48.8% in Group B, and 65.6% in Group C. Mean percentage of trabecular bone formation and mechanical stiffness were highest in the cages filled with β-TCP and BMP-2. Combination of BMP to β-TCP may act as an osteoconductive and osteoinductive bone graft substitute in clinical spine surgery.
- 日本脳神経外科学会の論文
- 2004-05-15
著者
-
Iwata Hiroo
Department Of Reparative Materials Field Of Tissue Engineering Institute For Frontier Medical Scienc
-
TAKI Waro
Departments of Neurosurgery, Kyoto University School of Medicine
-
OHYAMA Takashiro
Department of Neurosurgery, Mie University School of Medicine
-
KUBO Yoshichika
Department of Neurosurgery, Neuroscience Center, SaJcakibaraonsen Hospital
-
Taki Waro
Department Of Neurological Surgery Kitano Hospital
-
Kubo Yoshichika
Department Of Neurosurgery Neuroscience Center Sakakibaraonsen Hospital
-
Ohyama Takashiro
Department Of Neurosurgery Mie University School Of Medicine
関連論文
- Clinical Usefulness of the Dipole Tracing Method for Localizing Interictal Spikes in Partial Epilepsy
- Glucose Consumption and Rate Constants for ^<18>F-fluorodeoxyglucose in Human Gliomas
- Regional Cerebral Blood Flow and Oxygen Metabolism in Normal Pressure Hydrocephalus after Subarachnoid Hemorrhage
- Detachable Balloon Catheter Systems for Embolization of Cerebrovascular Lesions
- Experimental Studies in Nonsuture End-to-side Microvascular Anastomosis
- Basilar Bifurcation Aneurysms : Endovascular Treatment Versus Craniotomy
- A Surgical Treatment of "Moyamoya" Disease "Encephalo-Myo Synangiosis"
- Vascular Endothelial Growth Factor Immobilized on Platinum Microcoils for the Treatment of Intracranial Aneurysms: Experimental Rat Model Study
- β-Tricalcium Phosphate Combined With Recombinant Human Bone Morphogenetic Protein-2 : A Substitute for Autograft, Used for Packing Interbody Fusion Cages in the Canine Lumbar Spine
- β-Tricalcium Phosphate Combined with Recombinant Human Bone Morphogenetic Protein-2 : A Substitute for Autograft, Used for Packing Interbody Fusion Cages in the Canine Lumbar Spine
- An Osteoblast Differentiation Promoting Compound, TAK-778, combined with β-Tricalcium Phosphate used for Packing Interbody Fusion Cages
- Effect of Cation Content of Polycation-type Gene Carriers on in vitro Gene Transfer
- Successful Subcutaneous Pancreatic Islet Transplantation Using an Angiogenic Growth Factor-Releasing Device
- Low-frequency Electric Cortical Stimulation Has an Inhibitory Effect on Epileptic Focus in Mesial Temporal Lobe Epilepsy
- Management of Asymptomatic Cerebral Aneurysms Based on the Treatment Results of Recent 5 Years
- Endovascular Treatment of a Partially Thrombosed Giant Basilar Tip Aneurysm Using Interlocking Detachable Coils : Case Report
- Cerebral Ischemic Lesions Detected With Diffusion-Weighted Magnetic Resonance Imaging After Carotid Artery Stenting : Comparison of Several Anti-embolic Protection Devices
- Use of Cavernous Sinus EEG in the Detection of Seizure Onset and Spread in Mesial Temporal Lobe Epilepsy
- Scalp-Recorded, Ictal Focal DC Shift in a Patient with Tonic Seizure
- "Cavernous Sinus EEG": A New Method for the Preoperative Evaluation of Temporal Lobe Epilepsy
- Subdural Recording of Ictal DC Shifts in Neocortical Seizures in Humans
- Improved Provocative Test for the Embolization of Arteriovenous Malformations : Technical Note
- Treatment of Unclippable Giant Posterior Cerebral Artery Aneurysms with Detachable Balloons : Report of Three Cases
- Intra-abdominal Cyst Following Revision of Ventriculoperitoneal Shunt : Case Report
- Interventional Neuroradiological Techniques for the Treatment of Aneurysms of the Supra-aortic Extracranial Arteries
- Traumatic Carotid-Cavernous Fistula Identified by Three-dimensional Digital Subtraction Angiography
- Emerging Symptoms of Growing Skull Fracture after Secondary Trauma in an Adult : Case Report
- Fatal Subarachnoid Hemorrhage Due to Ruptured Infundibular Widening of the Posterior Communicating Artery : Case Report
- Intramedullary Spinal Cord Arteriovenous Malformation with Hematomyelia without Subarachnoid Hemorrhage : Case Report
- Aneurysm of the Cervical Internal Corotid Artery Associated with Marfan's Syndrome : Case Report
- Persistent Trigeminal Artery Associated with Brainstem Infarct : Case Report
- Endovascular Treatment for a Ruptured Persistent Trigeminal Artery Variant Aneurysm on the Distal Portion
- Preoperative Embolization of Upper Cervical Cord Hemangioblastoma Concomitant With Venous Congestion
- Posterior Fossa Arteriovenous Malformation Associated with Persistent Primitive Trigeminal Artery : Case Report
- Giant Internal Carotid Artery Aneurysm Manifesting as Difficulty in Swallowing : Case Report
- Cerebrospinal Fluid Rhinorrhea Associated with Untreated Prolactinoma : Case Report
- Memorial Review Celebrating the 50th Year of Publication of NMC : Neuroendovascular Therapy
- Acquired Intraventricular Arachnoid Cyst of the Third Ventricle : Case Report
- Changes in Hemodynamics After Placing Intracranial Stents
- Recent Trends in Neuroendovascular Therapy in Japan: Analysis of a Nationwide Survey—Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2
- Changes in Hemodynamics After Placing Intracranial Stents