Discrepancy Between [^<18>F]fluorodeoxyglucose and ^<11>C-methionine Positron Emission Tomography Findings in Sturge-Weber Syndrome(Case Report)
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概要
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Cerebral blood flow and metabolism were evaluated in an adult with symptomatic intractable epilepsy and Sturge-Weber syndrome (SWS) manifesting as angiomas in the left cerebral hemisphere. ^<99m>Tc-ethylcysteinate dimer single photon emission computed tomography detected reduced blood flow in the entire left cerebral hemisphere, and [^<18>F]fluorodeoxyglucose positron emission tomography (PET) showed decreased glucose metabolism in the left cerebral hemisphere. These findings indicated hypofunction of the left cerebral hemisphere, which caused the right hemiparesis. ^<11>C-methionine (^<11>C-Met) PET revealed high ^<11>C-Met accumulation in the angiomas in the left cerebral hemisphere. Immunostaining for glial fibrillary acidic protein showed positive reaction in the lesions. Gliosis is a likely mechanism for the ^<11>C-Met accumulation, which is possibly associated with progressive calcification in the angiomas and retarded growth of patients with SWS occurring over many years.
- 日本脳神経外科学会の論文
- 2003-09-15
著者
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ICHINOSE Tsutomu
Department of Neurosurgery, Osaka City University Graduate School of Medicine
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OHATA Kenji
Department of Neurosurgery, Osaka City University Graduate School of Medicine
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Takami Toshihiro
Department Of Neurosurgery Suisyoukai Murata Hospital
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Ohata Kenji
大阪市立大学 医学研究科脳神経外科学
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Seki S
Department Of Nuclear Medicine Osaka City University Graduate School Of Medicine
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SHIOMI Susumu
Department of Nuclear Medicine Graduate School of Medicine, Osaka City University
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TSUYUGUCHI Naohiro
Department of Neurosurgery, Osaka City University Graduate School of Medicine
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KAWABE Joji
Department of Nuclear Medicine, Osaka City University Medical School
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SUNADA Ichiro
Department of Neurosurgery, Saiseikai Ibaraki Hospital
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MORINO Michiharu
Department of Neurosurgery, Osaka City University Graduate School of Medicine
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HARA Mitsuhiro
Department of Neurosurgery, Osaka City University Graduate School of Medicine
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Sunada Ichiro
Department Of Neurosurgery Graduate School Of Medicine Osaka City University
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Sunada Ichiro
Department Of Neurosurgery Baba Memorial Hospital
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Hara Mitsuhiro
Department Of Neurosurgery Osaka City University Graduate School Of Medicine
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Hara Mitsuhiro
Department Of Neurosurgery Kyorin University School Of Medicine
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SHIMONISHI Yoshihiro
Department of Nuclear Medicine, Oska City University Graduate School of Medicine
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Tsuyuguchi Naohiro
Department Of Neurosurgery Osaka City University Graduate School Of Medicine
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Morino Michiharu
Department Of Neurosurgery Osaka City University Graduate School Of Medicine
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Takami Toshihiro
Department Of Neurosurgery Osaka City University Graduate School Of Medicine
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Takami Toshihiro
Department Of Mechanical Engineering Faculty Of Engineering Okayama University Of Science
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Shimonishi Yoshihiro
Department Of Nuclear Medicine Graduate School Of Medicine Osaka City University
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Shiomi Susumu
Third Department Of Internal Medicine Osaka City University Medical School
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Kotani Jin
Department Of Nuclear Medicine Osaka City University Graduate School Of Medicine
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Kawabe Joji
Department Of Nuclear Medicine Osaka City University Graduate School Of Medicine
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Kawabe J
Division Of Nuclear Medicine Osaka City University Medical School
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Shiomi Susumu
Department Of Hepatology Graduate School Of Medicine Osaka City University
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Takami Toshihiro
Departments Of Neurosurgery Neurology And Pediatrics Osaka City University Graduate School Of Medici
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Hara Mitsuhiro
Department Of Neurosurgery Osaka City University Medical School
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Ohata Kenji
Department Of Neurosurgery Graduate School Of Medicine Osaka City University
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Suehiro Shigefumi
Osaka City Univ.
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Ichinose Tsutomu
Department Of Neurosurgery Osaka City University Graduate School Of Medicine
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Tsuruno Takashi
Department Of Neurosurgery Suisyoukai Murata Hospital
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Tsuruno Takashi
Department Of Neurosurgery Suishokai Murata Hospital
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Hara Mitsuhiro
Departments Of Neurosurgery Neurology And Pediatrics Osaka City University Graduate School Of Medici
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