Differentiation of Pituitary Adenomas From Other Sellar and Parasellar Tumors by ^<99m>Tc(V)-DMSA Scintigraphy
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概要
- 論文の詳細を見る
Pentavalent technetium-99m dimercaptosuccinic acid [^<99m>Tc(V)-DMSA] scintigraphy was evaluated for the differentiation of pituitary adenomas, especially non-functioning adenomas, from other sellar and parasellar lesions. Diffuse ^<99m>Tc(V)-DMSA accumulation within the tumor was found in seven of seven non-functioning, three of four growth hormone-secreting, and seven of eight prolactin-secreting adenomas, but only partial accumulation in only two of 16 non-pituitary adenomas and normal pituitary glands. There were no significant relationship between tumor-to-background ratios and tumor size or serum hormone level. ^<99m>Tc(V)-DMSA scintigraphy showed overall sensitivity of 81% (17/21 cases) for detecting pituitary adenomas, in particular 100% for non-functioning adenomas. ^<99m>Tc(V)-DMSA maybe useful for detecting pituitary adenomas, especially non-functioning adenomas, and for the differentiation of non-functioning pituitary adenomas from other sellar and parasellar lesions.
- 日本脳神経外科学会の論文
- 2003-04-15
著者
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YAMAMOTO Isao
Department of Neurosurgery, Yokohama City University School of Medicine
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Kojima Yasuhiro
横浜南共済病院
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SUZUKI Shinichi
Department of Cardiovascular Surgery, Yokohama City University School of Medicine, Cardiovascular Ce
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Yamamura Koji
Department Of Neurosurgery Yokohama City University Medical Center
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Yamamoto Isao
Department Of Electronic Engineering Faculty Of Engineering Okayama University Of Science
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Suzuki Shinichi
Department Of Neurosurgery Yokohama City University
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Suzuki Shinichi
Department Of Aeronautical Engineering Nagoya University
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