ウィルムス腫瘍長期生存者における晩期障害としての背部変形の検討(I 主要疾患の遠隔成績, 25周年記念シンポジウム論文)

概要

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The development of scoliosis in the long term survivor who has received radiotherapy for Wilm's tumor is investigated using the various methods. of 28 children treated for Wilms's tumor at the university of Chiba hospital, 9 survived 10 years. The standard treatment consisted of nephrectomy, postoperative irradiation and Actinmycin-D protocol. As would be expected when large doses of ionizing irradiation have been deliverred to young children, postual changes were obseoved in years. These late effects in 5 children were investigated by Moire topography, Magnetic resonance image, and Spinal evoked response with the ordinary roentgenogram of spine. Roentgenogram showed the mild scoliosis with bony changes. Moire topography revealed 10-45mm hump and 40-90 waist line assymmetric index. MRI examination demonstrated clearly the atrophic changes of soft tissues, especilly subcutaneous fat and muscles. Abnormal neurolgical changes were not found in the Spinal evrked response. As a result, the bony changes could not be the only region to contributs the formation of scoliosis. Further investigation would be necessary to proove the rationale of the postual deformity using these modalities in future.
日本小児外科学会の論文
1989-10-20