教室における先天性胆道閉鎖症の検討 : 黄疸消失例を中心に

概要

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Twenty-five patients with congenital biliany atresia were experienced in our department from 1970 to 1982. In 13 (52%) out of 25 patients their jaundice had been disappeared postoperatively and 7 cases are living without jaundice. Six out of those 7 patients were particularly reviewed in this paper. The results are summerized as follows: 1) Elevation of serum alkaline phosphatase and LDH was observed in all cases. 2) The hepatobiliary scintigrams with <99m>^Tc-EHIDA in two cases with portal hypertension showed a poor liver uptake and the delayed excretion of RI from the liver. 3) In the 2 cases above mentioned, the percentage of sulfated bile acid to total bile acid in urine was 12% and 22% respectively, and those were lower compared to the other four cases. It is suggested that urinary sulfated bile acid may be more sensitive index than conventional liver function testes for biliary atresia. 4) The fecal fatty acid concentrations in 6 cases ranged from 0.2 to 1.2 g/day. A steatorrhea was not observed in those cases.
日本小児外科学会の論文
1984-04-20