Equilibrium and Kinetic Aspects on Protein Folding by the Diffusion-Collision Model
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概要
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A simple model of small globular proteins is studied for an examination of adiffusion-collision mechanism in a folding and unfolding transition. The modelconsists of two structural domains. Hydrogen bondings and hydrophobic infer-actions are considered. The stability of proteins depends on the balance betweenthese noncovalent interactions. The dependences of these interactions on fern-perature are different. Results obtained here are in good agreement with theexperimental data on the temperature dependence of specific heats and kinetic rateconstants.
- 社団法人日本物理学会の論文
- 1985-06-15
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