Donaggio反応陽性をもたらす血中蛋白細分画について

概要

論文の詳細を見る
Up to date Donaggio reaction positive substances from serum as well as urine had been already clarified to be glycoprotein, mainly a globulin region. The purpose of this study was to investigate the relation between serum protein-subfractions and Donaggio reaction positive substances, Used serum protein was separated to 30 minor parts by means of starch electrophoresis. The obtained summary was as follows ; 1) Almost all serum protein-subfractions had Donaggio titer, but albumin and a globulin regions were guessed to be main parts. 2) Albumin region had high Donaggio titer and specific activity (Donaggio titer / total protein), but they will be lost by deproteinization in practical Donaggio measuring. 3) Specific activity of serum subfraction was maximum in α_1 blobulin region. Donaggio reaction (nondeproteinization) positive substances in serum were anode side than haptoglobin or α_2-HS glycoprotein. 4) It was seemed that α_1-AG (α_1-acid glycoprotein) occupied main parts of al globulin region, as Donaggio reaction positive substance.
日本体力医学会の論文
1980-09-01