Thiamine Tetrahydrofurfuryl Dislfide(TTFD)の体力、特に筋力に及ぼす効果について : 二重盲検比較対照試験による検討

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The effect of TTFD chiefly on muscle strength in athletes, mainly track and field, in training camp was examined. The double-blind method was used. The test group (T-group) was given 150 mg/day of TTFD while the control group(P-group) was given 3 mg/day of TTFD. The duration of administration was two weeks. The following results were obtained. 1) In the following test items, T-group(150mg/day) showed higher values than =P-group(3mg/day) in a significant difference: sargent test (morning) at 5% level sargent test (evening) at 2.5% level left grip strength (evening) at 5% level right grip strength (morning) at 10% level No significant differences were found in other test items. 2) In the P-group, difference between 2 week stage (non-treated period) ant 4 week stage(treated period) was observed to have a trend for decline in the various test items. On the contrary, in the T-group, no decline was observed and a tend for a rise was found in all test items. 3) No adverse effects attributable to TTFD were noted with administration of 3mg/day nor 150mg/day for 2 weeks. 4) The influence of administration TTFD 150mg/day was discussed on effectiveness of training as shown by the increase of motor ability.
日本体力医学会の論文
1972-03-01