漸増運動による筋内pHの低下と過剰CO_2排出量との関係

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A study was conducted to investigate using ^<31>P NMR the relationship between the total excess volume of CO_2 output(CO_2 excess)due to bicarbonate buffering of lactic acid produced in exercise and the decrease of intracellular pH during incremental exercise. Five sprinters and 5 joggers performed incremental exercise to exhaustion on an bicycle ergometer. The values of CO_2 excess and CO_2 excess per body weight(CO_2 excess/W) were not different between the sprinters(2388±659ml, 36.7±8.5ml・kg^<-1>) and the joggers(2275±278ml, 40.0±6.3ml・kg^<-1>). Below the ventilatory threshold(VT), from VT to the respiratory compensation point (RCP), and above RCP the V_<O2>-V_<CO2> slopes were not different between the sprinters and the joggers, respectively (0.95±0.05 vs 0.95±0.06, 1.21±0.11 vs 1.30±0.14, 1.69±0.24 vs 1.76±0.18). However, the joggers showed significantly higher CO_2 excess/W per blood lactate accumulation(〓La) in exercise (CO_2 excess/W/〓La, 5.34±0.32ml・kg^<-1>・mmol^<-1>・l^<-1>)than the sprinters (4.50±0.14ml・kg^<-1>・mmol^<-1>・l^<-1>). The decrement of intracellular pH during incremental exercise showed a tendency to be smaller in joggers (0.63±0.18 pH unit) than in sprinters (0.83±0.10 pH unit), although there was no significant difference between the two groups. The values of CO_2 excess/W/〓La were correlated with the decrease of intracellular pH(r=-0.792, p<0.01). It is suggested that CO_2 excess/W/〓La reflects the efficiency of the bicarbonate buffering system, and could be an important factor influencing the decrease of intracellular pH due to lactate production.
日本体力医学会の論文
1993-02-01

漸増運動による筋内pHの低下と過剰CO_2排出量との関係

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