[SHORT REPORTS]Species Differences between Rabbits and Cats in their Respiratory Responses to Muscle Thin-Fiber Afferents
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概要
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Electrical stimulation (ES) of the muscle thin-fiber afferents causes respiratory facilitation during ES and is followed by respiratory suppression after the cessation of the stimulation in cats. To investigate this respiratory suppression, we need experimental animals in that this phenomenon is more clearly observed. In this study, we examined whether this respiratory suppression could be induced in rabbits. We first established the protocol outlining the adequate conditions for ES in rabbits to induce respiratory facilitation during ES. This was established as 400 times a muscle twitch threshold set at 8.3Hz for 30 sec. Despite these parameters, we did not observe andy reflex respiratory suppression after ES in rabbits. It seems reasonable to conclude, therefore, that the rabbit is not an animal species suitable for studies on reflex respiratory suppression.
- 名古屋大学の論文
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