EFFECT OF DIETARY CADMIUM ON SERUM AND LIVER LIPIDS IN MICE IN RELATION TO INTERACTION OF ESSENTIAL METALS, ZINC, COPPER AND IRON
スポンサーリンク
概要
- 論文の詳細を見る
Male ICR mice were given dietary Cd at three different levels (50, 100 and 200 ppm) for 85 days. At the end of this period, they showed a marked accumulation of Cd in the liver and kidney. In addition, there was also an increase in Zn and a decrease in Fe in these organs. The concentration of Cu in these organs; however remained unchanged. Serum cholesterol decreased in the Cd-100 and Cd-200 groups, but hepatic cholesterol did not. There was a positive correlation between serum cholesterol and serum Cu or Zn but not between serum cholesterol and serum Zn/Cu. Serum triglyceride was increased slightly but not dignificantly by the Cd exposure. A significant negative correlation between serum and hepatic triglyceride was found. These alterations of serum and hepatic lipids were discussed in relation to the essential metals (Cu, Zn and Fe).
- 日本トキシコロジー学会の論文
- 1984-02-25
著者
-
SUGAWARA Naoki
Department of Environmental and Public Health, Sapporo Medical College
-
Sugawara Naoki
Department Of Public Health Sapporo Medical College
-
SUGAWARA Naoki
Department of Public Health, Sapporo Medical College
関連論文
- TIME DEPENDENT EFFECTS OF SELENIUM ON CADMIUM-INDUCED AUTE MOUSE TESTICULAR DAMAGE
- INFLUENCE OF CADMIUM ON ZINC DISTRI BUTION IN THE MOUSE LIVER AND KIDNEY : ROLE OF METALLOTHIONEIN (The Fourth Meeting for the Study of Toxic Effect)
- EFFECT OF DIETARY CADMIUM ON SERUM AND LIVER LIPIDS IN MICE IN RELATION TO INTERACTION OF ESSENTIAL METALS, ZINC, COPPER AND IRON
- SELENIUM PROTECTION AGAINST TESTICULAR LIPID PEROXIDATION FROM CADMIUM
- ZINC DISTRIBUTION AND METALLOTHIONEIN IN THE LIVER AND KIDNEY OF MICE TREATED WITH CADMIUM
- Effect of Simultaneous Preinjection of Cadmium and Selenium on Hepatic and Testicular Dysfunction Caused by a Subsequent Challenge Dose of Cadmium