MICROSOMAL INJURY IN THE LIVER OF RATS TREATED WITH CARBON TETRACHLORIDE
スポンサーリンク
概要
- 論文の詳細を見る
The oral administration of CCl_4 (2.5 ml/kg) to male rats induced increase in the activity of serum GPT, accumulation of hepatic triglyceride, accerelation or depression in the activities of microsomal enzymes, disaggregation of hepatic polyribosomes, and decrease in the ability of in vitro protein synthesis 0.5 hr after the intubation. When, however, a small dose of CCl_4 (0.25 ml/kg) were given, the defects in hepatic polyribosomes and mixed-function oxygenase system were most marked among the above toxic changes.
- 日本トキシコロジー学会の論文
- 1981-05-25
著者
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ITO Teruo
Department of Radiation Oncology, The Cancer Institute, Ariake Hospital of Japanese Foundation for C
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Ito Teruo
Department Of Cardiology Nagoya Daini Red Cross Hospital
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Ito Teruo
Department Of Toxicology And Microbial Chemistry Faculty Of Pharmaceutical Sciences Tokyo University
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