Efficacy of gentian violet in the eradication of methicillin-resistant Staphylococcus aureus from skin lesions
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概要
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The efficacy of gentian violet (Gv) in eradicating methicillin-resistant Staphylococcus aureus (MRSA) in decubitus ulcers was investigated. Decubitus ulcers (a total of 18 cases) were scrubbed with Gv aqueous solution 0.1% and ointment containing Gv 0.1% was applied daily. MRSA was not detected in these lesions for 3-34 days (average, 10.5±2.5 days) after the application of Gv ointment. Before this trial, all patients were treated with povidone-iodine and antibiotics; however, those treatments were not effective in eradicating MRSA from skin lesions. Skin irritation and other systemic side effects caused by Gv were not observed. Our data suggest that Gv is a useful agent for treatment of the decubitus ulcers infected with MRSA.
- 1996-03-25
著者
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Ohkuni H.
Division Of Immunology Institute Of Gerontology Nippon Medical School
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Saji M.
Section Of Pharmaceutics The First Hospital Of Nippon Medical School
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Taguchi S.
Section of Pharmaceutics, the First Hospital of Nippon Medical School
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Uchiyama K.
the Second Department of Surgery, the First Hospital of Nippon Medical School
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Osono E.
Department of Second Internal Medicine, the First Hospital of Nippon Medical School
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Hayama N.
Department of Second Internal Medicine, the First Hospital of Nippon Medical School
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Osono E.
Department Of Second Internal Medicine The First Hospital Of Nippon Medical School
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Hayama N.
Department Of Second Internal Medicine The First Hospital Of Nippon Medical School
関連論文
- Efficacy of gentian violet in the eradication of methicillin-resistant Staphylococcus aureus from skin lesions
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