AB-PC軟膏のS. faecalisに対する発育阻止濃度測定

概要

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It was found that a 10% AB-PC ointment prepared at this hospital pharmacy demonstrated a remarkable effect on the erosion of woman's vulva. Study was made to determine MIC of AB-PC ointment against phlogistic Streptococcus faecalis. Hitherto, an injection system has been used for determination of MIC of antibiotics .In this study, we tried to use ointment itself in vitro to determine MIC of AB-PC ointment. a) 34 strains of S. faecalis were inoculated individually into AB-PC ointments in different concentrations which were laminated on HIA. b) The AB-PC ointments in different concentrations were laminated on the strains in the same number which were inoculated individually into HIA. MIC determined by both methods, a) and b), was 0.32%. Method a) was technically simpler and easier than method b) therefore, this method can be fully applied for hospital pharmacy to set up and prepare the most effective concentration of antibiotic ointments.
日本医療薬学会の論文
1985-10-20