注射用アンピシリンナトリウムの他剤混合時における力価の変化

概要

論文の詳細を見る
The potency of ampicillin is known to be reduced when mixed with glutathione. Halogen or sulfonic acid group is related to the detoxification mechanism of Tathion. In this study, mixtures were prepared first by dissolving Tathion in halogen-or sulfonic acid group-containing injections such as Allergin, Metilon and Adona. Then the effect of Viccillin for injection, an ampicillin preparation, added to the mixtures, was examined by bioassayand colorimetry. It was found that the potency of Viccillin is well preserved by adding Allergin, Metilon or Adona mixed with Tathion.
日本医療薬学会の論文
1980-02-20