ウロキナーゼ活性におよぼすアミノ酸輸液の影響

概要

論文の詳細を見る
No visible change was recognized in urokinase when dissolved in amino acid infusion, But the fibrinolytic activity of urokinase decreased immediately and gradually after the dissolution in any test by the tube, standard plate and Chandler's loop methods. It was found that the decrease in the fibrinolytic activity was due to lysine and sodium sulfite contained in the amino acid infusion. Then, the activity of urokinase was determined by the tube method after urokinase solution containing lysine or sodium sulfite was dialyzed, Urokinase in the presence of lysine showed activity stronger, to some extent, than the control, while the substance in the presence of sodium sulfite demonstrated great, irreversible loss of the activity.
日本医療薬学会の論文
1976-08-20