変異原研究領域におけるレギュラトリーサイエンスの確立 : 第29回大会受賞講演

概要

論文の詳細を見る
"Regulatory sciences" are defined as "sciences to regulate results obtained from basic research fields for practical use in human society" . Since not all products of basic research will be useful to society, it is important to be able to select those products which are most likely to be useful Furthermore, while some products may be profitable, thery may be hazardous to humans if handled in appropriately. Therefore, it is important to have processes to evaluate the relative merits of accumulated basic research results, even though such processes may have some limitations. For highly accurate prediction or extrapolation beyond such results, one majior requirement is an extensive and high quality database that will help generate "standards (guidelines) for evaluation" with consensus from the regulatory, academic and industry sides. However, it is difficult to establish such a database in basic research fields and relatively large collaborative studies with cooperation of the regulators, academic and industry are essential to establish such database. The achievements in several intra/international collaborative studies on the mouse micronucleus tests, the chromosomal aberration and micronucleus tests using cultured mammalian cells, and the mouse lymphoma tk assays, are introduced to demonstrate their usefulness in the regulatory sciences.
日本環境変異原学会の論文
2001-06-30