遠心ポンプ-人工肺一体型PCPSシステムの開発
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概要
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The present paper deals with development of an all-in-one PCPS (Percutaneous Cardio Pulmonary Support) system. The system consists of a pump-oxygenator unit and pump controller. The pump-oxygenator unit contains centrifugal pump and extracapillary flow type membrane oxygenator (O.8m^2) in one compact body. Dimensions of the pump-oxygenator unit are as follows : length : 250 mm : diameter : 90 mm ; weight : 1kg. The unit has priming volume of 250 ml. The in-vitro tests (gas exchange, fluid dynamic performance, hemolysis) and an ex-vivo test was conducted. The results are as follows : 1. Fluid dynamic : The system products 1. 6-3.8 l/min of flow against 100 mmHg of outlet pressure at a rotation speed of 2500 to 3500 rpm. 2. Hemolysis : The increase rate of plasma free hemoglobin was 22 mg・dl^<-1>/h with the PCPS system. 3. Gas exchange : O_2 transfer rate of the system was 180 ml/min and CO_2 transfer rate was 120 ml/min (V/Q= 1) at a blood flow rate 3l /min. 4. Ex-vivo test : The device was operable. In conclusion, the system is considered applicable to cardio pulmonary support.
- 公益社団法人精密工学会の論文
- 1993-06-05
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