断煙者のFEV_1/FVC(%)は, 喫煙者よりも低下しにくいのか?

概要

論文の詳細を見る
Though many epidemiologic studies have found a progressive relative loss of pulmonary function with cumulative smoking, other studies did not find that smoking cessation benefited pulmonary function. We therefore performed a cross-sectional study to see whether there was a major difference in the rate of decline in FEV_1/FVC(%) with aging between smokers and those who had ceased smoking. The subjects were 2,326 men who came to our hospital for their annual medical checkup from April 2000 to September 2001, consisting of 796 men who had never smoked, 819 current smokers and 711 former smokers. Current smokers and former smokers showed significantly bigger declines in FEV_1/FVC(%) than subjects who had never smoked. In the comparison of FEV_1/FVC(%) between current smoker and former smokers, we divided the former smokers group into 2 groups according to whether they had stopped smoking less than 5 years ago or 5 or more years ago. However, in neither of these two groups was there a significantly difference in decline in FEV_1/FVC(%) as compared to the smokers group, suggesting that smoking cessation did not slow the rate of decline in FEV_1/FVC(%) with aging. Recently, more and more people have been giving up smoking after their medical checkup. The next step is to provide them with FEV_1 and other useful data besides FEV_1/FVC(%) to give them the incentive to stay off cigarettes.
日本医療薬学会の論文
2005-03-10