Anorexia nervosa の認知障害と事象関連電位-(P300)

概要

論文の詳細を見る
To evaluate the cognitive function in anorexia nervosa (AN), P300 component of event-related potential (ERP) was measured, using odd-ball paradigm, in 10 females with AN and 10 healthy young female controls. The P300 component was not detected in two of the patients with AN, but the remaining eight patients had a longer latency and bigger amplitude of P300 than the controls. The findings were not equivalent to those in psychiatric disorders such as manic depressive psychosis or borderline personality disorder. Together with the present and previous studies on pathophysiological implications of P300 component, P300 abnormality seems to be due to distorted cognition of patients with AN. However, it still remains unclear whether P300 component plays a critical role in the evaluation of cognitive function in AN. In comparison with other results, further studies on the implications of P300 abnormality will be necessary for a step toward its certification.
日本心身医学会の論文
1990-01-08