チャイロコメノゴミムシダマシ幼虫の腹部縦走筋における抑制性のグルタミン酸応答

概要

論文の詳細を見る
To study the inhibitory mechanisms of the ventral longitudinal muscle fibers of the mealworm larva Tenebrio molitor, the effects of several inhibitory compounds on the excitatory post-synaptic potentials (EPSPs), membrane potentials and L-glutamate-induced potentials (GLU-Ps) were investigated by means of a microelectrode. Application of GABA, glycine, L-α-alanine, β-alanine, taurine and picrotoxin were used in the muscle preparations. None of these compounds had an effect on the EPSP and membrane potentials. In contrast, GLU-Ps were potentiated by picrotoxin, GABA_A antagonist and chloride channel blocker, whereas GABA, glycine, L-α-alanine, β-alanine and taurine had no effect. This potentiation of GLU-Ps may result from a blockade of glutamate-gated chloride channels by picrotoxin. These results suggested the presence of extrajunctional chloride-channel-type glutamate receptors in the ventral longitudinal muscle fibers of the larval mealworm. A similar result was obtained with a glutamate agonist, quisqualate, suggesting the chloride channel may be under the control of a quisqualate like receptor.
日本応用動物昆虫学会の論文
2002-08-25