(松本大学地域総合研究センター研究員研究業績)
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概要
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Background/Aims: This study was carried out to reveal the relationships between iron deficiency anemia and the results of an immunochemical fecal occult blood test, iron deficiency anemia and colorectal cancer. Materials and Methods: Seventeen thousand and six hundred sixty four asymptomatic individuals were subjects of this study. They gave samples for an immunochemical occult blood test, and colonoscopy was carried out during a medical check-up. The subjects were divided into two groups, according to the laboratory findings on iron deficiency anemia, and the positivity rate of an immunochemical occult blood test as well as the detection rate for colorectal cancer were compared in the two groups. In addition, the detection rate for colorectal cancer were determined in four groups stratified by both the results of occult blood test and the presence of iron deficiency anemia. Results: The occult blood test was positive in 18.4% and 3.8% of subjects with andwithout iron deficiency anemia, and the detection rate for colorectal cancer was 2.7% and 0.4% in subjects with and without iron deficiency anemia, respectively, indicating a significant difference in the positivity rate (P<0.001) as well as the detection rate (P<0.05) between the two groups. The detection rate for colorectal cancer was highest in subjects with iron deficiency anemia with a positive occult blood test, respectively. Conclusions: These results suggest that there are positive associations between iron deficiency anemia and the results of an immunochemical occult blood test, and between the patients with iron deficiency anemia and colorectal cancer, and that colonoscopy is necessary particularly in cases where the immunochemical occult blood test is positive and there is a finding of iron deficiency anemia.
- 松本大学の論文
- 2002-10-01