Optically Active 1-Hydroxy-3-Substituted Succinimides for Enantioselective Peptide Synthesis

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概要

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• Optically active 1-hydroxy-3-substituted succinimides were prepared in good yield. The enantioselectivity was evaluated based on specific rotation of dipeptides. 1-Hydroxy-3-substituted succinimide esters of Z-alanine were treated with D, L-ethyl alaninate to indicate 70 and 90% diastereomeric excess of L-L and D-D isomers respectively.

• 東京工芸大学の論文

著者

• Okawara Makoto

  Professer Research Laboratory Of Resources Utilization Tokyo Institute Of Technology

• Teramoto Takero

  Lecture Master Course Fellow And Professer Department Of Ndustrial Chemistry

• Kurosaki Toshikazu

  Lecture Master Course Fellow And Professer Department Of Ndustrial Chemistry

• DEGUCHI Mikito

  Lecture, Master Course Fellow and Professer,Department of ndustrial Chemistry

• Deguchi Mikito

  Lecture Master Course Fellow And Professer Department Of Ndustrial Chemistry

関連論文

• Acetohydroxamic Acid for Peptide Synthesis
• Optically Active 1-Hydroxy-3-Substituted Succinimides for Enantioselective Peptide Synthesis
• Enantioselective Peptide Synthesis by Using the Optically Active Polymer Containing the 1-Benzyl-3-Hydroxy-5-Isobutyl-Hydantoin Structure

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