<ORIGINAL REPORT>STUDIES ON LYMPHOID TISSUE DAMAGE WITH A TOXIC PHYTOHEMAGGLUTININ AND ITS SUBFRACTIONS IN MICE

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概要

• 論文の詳細を見る

• この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。PHAs prepared from red kidney beans in the laboratory were tested in hemagglutinating, blastogenic and toxic activities and found to be more potent in these activities than PHA-P (Difco). Especially, our PHAs showed prominent toxicity to mice. An intraperitoneal application of 2 mg of PHA (Bo) or PHA (Ba) was enough to kill adult mouse and caused severe damage in lymphoid tissues. The "conversion" of cellularity in the thymus and marked depression of lymphoid elements with intensive hemorrhage were observed histologically as signs of toxicity. PHAs were further investigated by CM-cellulose column chromatography. Toxic component could be separated from the fraction furnished with hemagglutinating activity or blastogenic activity.

• 京都大学の論文
• 1976-03-30

著者

• BABA MITSUO

  Department of Pathology, Chest Disease Research Institute, Kyoto University

• Baba Mitsuo

  Department Of Pathology Chest Discase Research Institute Kyoto University

• Baba Mitsuo

  Department Of Bacteriology And Department Of Pathology Chest Disease Research Institute Kyoto Univer

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• Immunohistochemical Studies on Lactate Dehydrogenase Subunits (II)
• Immunohistochemical Studies on Lactate Dehydrogenase Subunit (I)
• STUDIES ON LYMPHOID TISSUE DAMAGE WITH A TOXIC PHYTOHEMAGGLUTININ AND ITS SUBFRACTIONS IN MICE
• INHIBITORY ACTION OF PHA ON THE APPEARANCE OF THYMIC RETICULAR CELLS IN VITRO

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