<研究論文>生体組織のマイクロ波誘電分光と含水量測定

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We have proposed a new approach to determine water content for tissue in vivo through microwave dielectric measurements via a time domain reflectometry (TDR) method using flat-end probes. Dielectric spectra observed on human skin of finger were drastically changed by soaking in 37℃ water during 30 minutes because of change in water content. The high frequency relaxation process observed around 10GHz was due to reorientation of free water molecules, and the water content can be determined from the dielectric strength Δε_h. A recovery process of the skin was also observed, and time dependence of the water content was examined. On the other hand, the water content estimated from TDR measurements depended on weight of a slug that is one of the most useful samples to control the water content in vivo. Furthermore, the water content was detected on healing process of human skin of face damaged by hydrofluoric acid. During the first six days, the water content of the damaged skin was significantly lower than normal skin. This difference disappeared after twelve days, since the damaged tissue had healed up. The present work suggests that TDR measurement is useful and effective method to determine water content, and will be applicable to a diagnosis.
東海大学の論文