Procedures of amino acid sequencing of peptides in natural proteins collection of knowledge and intelligence for construction of reliable chemical inference system

概要

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In order to establish a reliable chemical inference system on amino acid sequencing of natural peptides, as various kinds of relevant knowledge and intelligence as possible are collected. Topics are on didemnins, dolastatin 3, TL-119 and/or A-3302-B, mycosubtilin, patellamide A, duramycin (and cinnamycin), bottoromycin A 2, A19009, galantin I, vancomycin, stenothricin, calf speleen profilin, neocarzinostatin, pancreatic spasmolytic polypeptide, cerebratulus toxin B-IV, RNAase U 2, ferredoxin II, SKO-III, bovine serum albumin, bovine pancrea DNase, porcine, bancreatic colipase, smallest unit of beef heart bc1 complex, papaya mosaic virus coat protein, human erythrocyte 2, 3-bisphosphoglycerate mutase, sialoglycoprotein D (glycophorin C), acidic phosphopase A 2, human big gastrin I, neuroparisons, bucillus subtillis glucose permease, His-rich protein from avian malaria parastite plasmodium lophurae, the Bacillus subtils spoVE locus predicted peptide, and prostatic spermine binding protein. All of them were involved in structure revision. The present paper deduced causes of discrepancies of intelligence, among biochemists, and proposed how to avoid such troubles which can be resolved by biochemists but are fatal for such a chemical inference system, in terms of informational chemistry, such as informational homology, and scoop-up and pick-up approaches.
1994-01-31