Genotype Determination of Hepatitis C Virus Strains in Malaysia
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概要
- 論文の詳細を見る
Out of 12 patient sera obtained from Malaysia, seven sera (7/12) were found to contain hepatitis C virus (HCV) genome by nested RT-PCR with universal HCV specific primers which were derived from 5' noncoding region (5' NCR). Genotype determination of these 7 Malaysian HCV strains were carried out both by subtype-specific core amplification system (Okamoto et al., 1992 and 1993) and sequencing in the 5' NCR. Four Malaysian strains were major genotype 1 (two of subtype II/1b, one of subtype I/1a and one of co-infection with I/1a + II/1b). The genotypes of 3 remaining strains were determined as major genotype 3 by nucleotide sequences in the 5' NCR. The results showed that HCV major genotype 1, 2 and 3 are common in the world, especially in Asian countries including Malaysia.
- 長崎大学の論文
著者
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Ayub Ali
Department Of Virology Institute Of Tropical Medicine Who Collaborating Center For Reference And Res
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Ali Ayub
Department Of Virology Institute Of Tropical Medicine Nagasaki University
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Futoshi Hasebe
Department Of Virology Institute Of Tropical Medicine Who Collaborating Center For Reference And Res
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Hasebe Futoshi
Department Of Virology Institute Of Tropical Medicine
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Wei-yun Zheng
Department Of Virology Institute Of Tropical Medicine Who Collabor-ating Center For Reference And Re
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Zheng Wei-Yun
Department of Virology,Institute of Tropical Medicine, WHO Collabor-ating Center for Reference and Research on Tropical Virus Diseases, Nagasaki University
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