血圧と心拍数の低周波ゆらぎとウルトラディアンリズム

概要

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Low-frequency fluctuations of arterial blood pressure (systolic blood pressure : SBP and diastolic blood pressure : DBP) and heart rate (HR) in humans are studied by spectral analysis. Using an automatic blood pressure recorder, SBP, DBP and HR are measured noninvasively at intervals of 2 min and 4 min for 7h and of 15 min for 35h. Power spectral density functions and cross-spectral density functions of SBP, DBP and HR are estimated by means of autoregressive (AR) models. Power spectra, calculated for SBP, DBP and HR via scalar AR model, reveal the existence of three kinds of ultradian rhythms with periods in the vicinity of 30 min, 60 min and 90 min, respectively. Coherence functions and phase spectra, calculated between SBP and HR via bivariate AR model, show a tendency that the variations of SBP and HR with periods longer than 90 min are in phase and strongly correlated. A power spectral density estimated from a long-term (35h) recording of SBP reveals the existence of 1/f fluctuations in the low frequency range of 10^-4-10^-3 Hz.
東海大学の論文