<原著>Diltiazemを用いた単純低温浸漬保存法による24時間心保存の研究 : 31-phosphorus nuclear magnetic resonanceによる評価

概要

論文の詳細を見る
The effect of the Ca-antagonist, diltiazem, on simple cold immersion preservation of the rabbit heart was examined. The viability of the heart was evaluated by the nuclear magnetic resonance spectroscopy. Myocardial viability was evaluated under the simple immersion in Euro-Collins solution at 4℃ for 12 and 24 hours. Furthermore high energy phosphate was evaluated in three cases. Diltiazem was added to the preservation solution, to the perfusate during the pre-ischemic period, or to the perfusate after the global ischemic period. By the pre-ischemic administration of the Ca-antagonist, the high energy phosphate after 24 hours was preserved equally as well that after 12 hours of preservation. In conclusion diltiazem was useful for preservation of the heart for a long period and high energy phosphate was preserved the most by its preischemic administration.
近畿大学の論文
1995-12-25