<原著>加令過程におけるラット横紋筋の神経筋接合部の形態学的変化について

概要

論文の詳細を見る
Morphological changes of end plates referred to aging were observed by means of light and electron microscopes. Examined muscle is the lateral head of gastrocnemius from total 12 rats which were subdivided into the age groups of 2.5,6,14 and 18 months. The following items were measured on electron microscopic pictures of end plate regions of each animal : 1. nerve terminal area, 2. mitochondrial area, 3. postsynaptic areas, 4. presynaptic membrane length, 5. postsynaptic membrane length, 6. mitochondrial diameter, 7. the number of mitochondria, 8. the number of synaptic vesicles. Morphological and morphometrical estimation of the end plate regions was performed by these data. Significant changes of axon terminals related to aging were noticed as the tendencies to decrease of the number of mitochondria, and to increase of the mitochondrial diameter associated with diminution of the cristae. The other alterations were appearances of myelin figures in the axon terminals, interposition of Schwann cell process, and empty folds of basement membrane. These were recognized in 14 and 18 months age groups. Although alteration of neurotrophism was suggested, examination of more older age groups is needed to clarify further details in relation to the alterations.
近畿大学の論文
1981-03-25