<原著>脳神経外科手術に於ける輸液療法の問題点について

概要

論文の詳細を見る
66 patients treated with intracranial operation (aneurysm 27,A-V malformation 10,brain tumor 17 and others) were clinically observed in several points of vital signs, in-out water balance and serum natrium under the infusion therapy performed during 3 days after surgery. These patients were devided into 3 groups, group I treated with lactated Ringer's solution, group II with low sodium solution and group III with lactated Ringer's and low sodium solutions. In the group I treated with lactated Ringer's solution, better results in all clinical points could be recognized. After intracranial operation, the function of osmoreceptor of the hypothalamus would be in disturbance and permeability of the Blood-Brain-Barrier would be increased. When the brain edema exists, water in the ICF space shoud be removed out and production of the non-functional ECF should be suppressed. Infusion agent should be selected for this purpose, to keep the homeostatic function about the osmotic pressure between the ICF and ECF.
近畿大学の論文
1976-12-28