<Original Report>DISTRIBUTION AND METABOLISM OF BENZO (a) PYRENE IN FETAL MOUSE

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概要

• 論文の詳細を見る

• この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。The distribution of benzo(a)pyrene given i. v. into a pregnant mouse was observed by macroautoradiography. Small amount of BP was transferred into fetus, indicating the highest concentration into the intestinal tract and next in the liver and kidneys in the fetus near term. However the lung was labeled very low in spite of the most susceptable organ in transplacental carcinogenesis. Radiometric analysis revealed that intact BP and its metabolites were detected in the fetal tissues during various developmental stages. Hydroxy compounds were metabolized into conjugated materials and excreted through the intestinal tract of the fetus near term.

• 京都大学の論文
• 1974-03-30

著者

• TAKAHASHI Gonya

  Department of Pathology, Chest Disease Research Institute, Kyoto University

• Takahashi Gonya

  Department Of Pathology Chest Disease Research Institute Kyoto University

関連論文

• LUNG TUMORS IN MICE SUCKLED BY 3-METHYLCHOLANTHRENE-TREATED MOTHERS
• MACROAUTORADIOGRAPHIC ASSAYS OF ^C-LABELED 4-NITROQUINOLINE 1-OXIDE IN ADULT AND FETAL MICE
• DISTRIBUTION AND METABOLISM OF BENZO (a) PYRENE IN FETAL MOUSE
• MACROAUTORADIOGRAPHIC STUDY OF THE DISTRIBUTION OF ^C-DIMETHYLNITROSAMINE IN MICE AND FETUSES
• FLUOROMETRIC MEASUREMENT OF 3-METHYLCHOLANTHRENE AND ITS METABOLITES IN TISSUE. I. MEASUREMENT OF 3-METHYLCHOLANTHRENE IN ORAGANIC SOLVENTS

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