Levels of Mercury in the Organs of Normal and Acatalasemic Mice Exposed to Metallic Mercury Vapor
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The levels of mercury in the organs of normal and acatalasemic mice exposed to metallic mercury vapor after administration of ethanol or aminotriazole was inves tigated. Levels of mercuric ion in the liver of normal and acatalasemic mice immediately and after 6 hours following exposure to metallic mercury vapor increased in order to mice pretreated with ethanol (ET), pretreated with aminotriazole (AT) and control mice, respectively. Levels of mercuric ion in the lungs of both mice after 6 hours following exposure to mercury vapor decreased than those of mice immediately after exposure. On the other hand, levels of mercuric ion in the liver of both mice pretreated with ethanol or aminotriazole was significantly higher than that of control mice, which indicated that catalase plays a role in oxidizing and taking up mercury. The amounts of metallic mercury in the arterial and orbital venous bloods of normal and acatalasemic mice exposed to metallic mercury vapor were investigated. The amounts of metallic mercury and ratios of metallic mercury to total mercury in the both bloods of acatalasemic mice were significantly higher than those of normal mice. On the other hand, the amounts of total mercury in the both bloods of normal mice were significantly higher than that of acatalasemic mice.
- 岡山理科大学の論文
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